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Seizures Seen With DTP, MMR Do Not Increase Neurodevelopmental Risks.(vaccine side effects)
2001 SEP 19 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Children who receive the diphtheria and tetanus toxoids and whole-cell pertussis (DTP) and measles, mumps, rubella (MMR) vaccines are at a significantly increased risk of febrile seizures, but these seizures apparently do not cause lasting harm, according to a new study in the New England Journal of Medicine.
William E. Barlow and colleagues with the Centers for Disease Control and Prevention Vaccine Safety Datalink Working Group reviewed medical records for children with seizures among 679,942 patients at four large health maintenance organizations who had received 340,386 DTP vaccinations, 137,457 MMR vaccinations, or no recent vaccination.
The researchers calculated the risk of febrile and nonfebrile seizures among these children and followed the ones with vaccine-related febrile seizures to identify the risk of subsequent seizures and other neurologic disabilities.
DTP vaccine carried an increased risk of febrile seizure only on the day of vaccination (adjusted relative risk 5.70), while MMR vaccine increased the risk of febrile seizures eight to 14 days after vaccination (relative risk 2.83), reported Barlow and coworkers. Neither vaccination was associated with an increased risk of nonfebrile seizures.
The number of febrile seizures attributable to DTP and MMR vaccines was estimated to be 6-9/100,000 and 25-34/100,000 children, respectively, the researchers said.
Although parents have been alarmed in recent years by reports of vaccine-induced autism and other permanent health problems, this study ...
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