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2001 SEP 12 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - The currently licensed meningococcal vaccine could have prevented 82.8% of invasive meningitis in Maryland young adults in the 1990s, epidemiologists there have found.
The 15- to 24-year-old age group accounted for nearly one-quarter of the 295 total cases and was most likely to have benefited from vaccination, found L.H. Harrison and colleagues at the University of Pittsburgh.
Their report of the incidence and outcomes for invasive meningococcal disease among Maryland residents during the 1990s found that 71 of 295 total cases occurred among those ages 15 through 24 years and that 16 (22.5%) of these cases were fatal. In this age group, the annual incidence rate increased from 0.9 to 2.1 cases per 100,000, and the proportion of all cases from 16% to 28.9%, before dropping again to 1.0 and 16.4% in 1998 through 1999, respectively.
Infection in 15- through 24-year-olds was more likely to be fatal than in younger patients (22.5% vs. 4.6%), noted Harrison and coworkers and compared with older adults was more likely to be associated with male sex (66.2% vs. 34.8%) and serogroup C infection (46.9% vs. 20.2%).
Young adults were most likely to have benefited from immunization with the meningococcal vaccine, said Harrison and team; it might have prevented 82.8% of cases in this group, compared with ...
Source: HighBeam Research, Vaccine Could Have Prevented Four Of Five Cases In Young...