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2001 AUG 23 - (NewsRx Network) - by N.R. Saltmarsh, staff medical writer - Obesity bumps up the risk for pregnant women and their fetuses, probably because of alterations in the metabolic state, say researchers working in London.
N.J. Sebire and colleagues, St. Mary's Hospital, evaluated outcomes for 287,213 completed singleton pregnancies, including 61.6% in normal-weight (body mass index [BMI] 20-24.9 at first visit), 27.5% in moderately obese (BMI 25-29.9), and 10.9% in very obese (BMI [greater than or equal to]30) women, for their study published in the International Journal of Obesity and Related Metabolic Disorders.
Compared with women who had normal BMI, the following outcomes were significantly more common in obese pregnant women (odds ratio for BMI 25-30 and BMI 30 respectively): gestational diabetes mellitus (1.68, 3.6), proteinuric pre-eclampsia (1.44, 2.14), induction of labor (2.14, 1.70), delivery by emergency cesarean (1.30, 1.83), postpartum hemorrhage (1.16, 1.39), genital tract infection (1.24, 1.30), urinary tract infection (1.17, 1.39), wound infection (1.27, 2.24), birth weight above the 90th percentile (1.57, 2.36), and intrauterine death (1.10, 1.40).
Heavier women were, however, less likely to deliver before 32 weeks' gestation (0.73, 0.81) compared with normal-weight women, reported Sebire and coworkers.
In all cases, increasing maternal BMI was associated with increased magnitude of risk, they said ("Maternal ...
Source: HighBeam Research, Higher BMI Means Greater Risk For Pregnant Women.(body mass index)