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2001 SEP 5 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Elderly travelers who are vaccinated against influenza before travel receive no additional benefit from a second vaccine 12 weeks later, researchers in Canada have found.
J.A. Buxton and associates compared the antibody responses of travelers (>=)65 after influenza vaccination and revaccination to those of age- and geography-matched controls who received only one vaccination.
There was no significant difference between log[10] hemagglutinin-inhibiting (HI) antibody titers or protective levels of HI antibody between 28 re-vaccinated and 28 control subjects, reported Buxton and coworkers.
Probable protection for influenza A antigens remained high 24 weeks after a single immunization and re-vaccination (A/Sydney/05/97 [H3N2], 92% and 96%, and A/Beijing/262/95 [H1N1], 80% and 96%, respectively), Buxton and colleagues found. A/Sydney antibody titer was lower with more times vaccinated in the previous five years, they added.
The second influenza vaccination was not associated with increased ...
Source: HighBeam Research, Second Influenza Vaccination Makes No Difference In Elderly...