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2001 AUG 9 - (NewsRx Network) -- Scientists in France have succeeded in using previously frozen ovarian tissue to produce live offspring in large mammals for the first time.
The team, led by Prof. Bruno Salle and Dr. Jacqueline Lornage of the Departement de Medecine de la Reproduction at the Hopital Edouard Herriot in Lyon, reported that from six ewes there had been four pregnancies that produced three live lambs: one lamb that died shortly after birth and twins that died after a premature delivery.
Salle and Lornage told the European Society of Human Reproduction and Embryology annual meeting that they believed this was the first report of live births in large mammals after using ovarian tissue which had been taken from the ewes, frozen and stored, then thawed and grafted back into the same sheep.
"These four pregnancies, after frozen ovarian autograft, give immense hope to women who become sterilized by cancer treatments," said Salle. "However we are not ready to try this technique in women yet, as first of all the procedure has to be repeated by ourselves and other researchers, and secondly, we need to discover how long the ovarian graft ...
Source: HighBeam Research, Scientists Report The First Live Births In Large Mammals After Using...