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C-Reactive Protein Correlates With Adiposity, HRT Use In Menopause.(hormone replacement therapy)
2001 AUG 9- (NewsRx Network) -- by N.R. Saltmarsh, staff medical writer - Levels of C-reactive protein are associated with weight gain, obesity, and use of hormone replacement therapy (HRT) in postmenopausal women, researchers in the United States have found.
E. Barinas-Mitchell and colleagues hypothesized that C-reactive protein levels would be higher among HRT users and among women with greater body mass index, waist circumference, or visceral fat. They evaluated measurements of body fat and C-reactive protein concentrations in 101 HRT users and 106 HRT nonusers who participated in the Healthy Women Study (Allegheny County, Pennsylvania, 1998).
The median levels of C-reactive protein were 3.01 mg/l in HRT users compared with 1.74 mg/l in nonusers, noted Barinas-Mitchell and coworkers. C-reactive protein concentrations were strongly positively correlated with body size, fatness, fat distribution, and weight gain among both groups of women ("Serum levels of C-reactive protein are associated with obesity, weight gain, and hormone replacement therapy in healthy postmenopausal women," American Journal of Epidemiology, 2001;153(11):1094-1101).
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