AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Metformin May Be Useful For PCOS Patients With Metabolic Syndrome Features.(polycystic ovary syndrome)
2001 AUG 9 - (NewsRx Network) -- by N.R. Saltmarsh, staff medical writer - A new report in the Medical Journal of Australia describes the potential therapeutic use of metformin for patients with polycystic ovary syndrome (PCOS) who also exhibit aspects of the metabolic syndrome, specifically glucose intolerance, type 2 diabetes, and hyperlipidemia.
Women with PCOS typically have, among other features, ovarian dysfunction and androgen excess, which may be due in part to hyperinsulinemia, explained R.J. Norman and colleagues in Australia. The oral hypoglycemic agent metformin, by addressing hyperinsulinemia, may resolve some other symptoms of PCOS, they proposed.
They pointed out that reducing insulin resistance through lifestyle modifications such as diet and exercise has been shown to improve endocrine and menstrual function in PCOS and thus it comes as no surprise that metformin reduces serum concentrations of insulin and androgens, reduces hirsutism, and to improves ovulation rates.
Although it is not known whether metformin can improve fertility problems experienced by PCOS patients, the drug may aid weight loss to a small extent by acting on visceral adipose tissue ("Metformin and intervention in polycystic ovary ...
- PCOS patients have increased risk of cardiovascular disease, studies show.
- Newspaper article from: OBGYN & Reproduction Week May 24, 2004 700+ words
...diabetes, obesity, CVD, and metabolic syndrome. Signs of PCOS include...sectional study of 116 PCOS patients and 94 controls matched...of CVD - are increased in PCOS patients. The researchers measured...indicated that 36.8% of PCOS patients had extremely high (above...
- Increased risk of cardiovascular disease shown in PCOS patients.
- Newspaper article from: Heart Disease Weekly June 6, 2004 700+ words
...diabetes, obesity, CVD, and metabolic syndrome. Signs of PCOS include...sectional study on 116 PCOS patients and 94 BMI (body mass index...of CVD - are increased in PCOS patients. The researchers measured...indicated that 36.8% of PCOS patients had extremely high ...
- Increased Risk of Cardiovascular Disease Shown in PCOS Patients.
- Press release article from: PR Newswire May 5, 2004 700+ words
...diabetes, obesity, CVD and metabolic syndrome. Signs of PCOS include...sectional study on 116 PCOS patients and 94 BMI-matched controls...CVD -- are increased in PCOS patients. The researchers measured...indicated that 36.8 percent of PCOS patients had extremely high ...
- Screen PCOS patients' sisters, mothers for diabetes. (Higher Androgen Levels,...
- Magazine article from: OB GYN News Kirn, Timothy F. September 15, 2002 700+ words
...The second study showed that about half of the sisters of PCOS patients who actually have polycystic ovaries--and high testosterone...The researchers used ultrasound to determine whether 134 PCOS patients had polycystic ovaries. They then compared testosterone...
- Test All PCOS Patients For Thyroid Disease.(Brief Article)
- Magazine article from: Family Practice News JANCIN, BRUCE October 1, 2001 700+ words
...mL were present in 10% of controls and in 43% (25) of PCOS patients; 20 of these 25 also had an abnormal thyroid ultrasound...thyroid hormone and TSH levels, however, were normal in all PCOS patients and controls. Women are known to have a 5- to 10-fold...
- Metformin & glitazones: do they really help PCOS patients? While the use of...
- Magazine article from: Journal of Family Practice Pillai, Anush S. Bang, Heejung Green, Charles June 1, 2007 700+ words
...caused by this syndrome. Objectives Our goal was to assess the evidence for the use of TZDs or metformin in the treatment of PCOS patients. In addition, we sought to assess and compare the effectiveness of metformin vs TZDs in the clinical and biochemical regression...
- Young PCOS patients show signs of arterial aging.(polycystic ovary syndrome )
- Magazine article from: Internal Medicine News Bates, Betsy September 15, 2005 700+ words
...determined that the best predictors of endothelial damage in PCOS subjects were elevated levels of testosterone and CRP. Young PCOS patients with high levels of both should be closely followed for cardiovascular consequences of the syndrome, particularly if they...
- Young, nonobese PCOS patients have cardiac risk.(Gynecology)
- Magazine article from: OB GYN News Kirn, Timothy F. October 15, 2004 700+ words
...carotid arteries to gauge intima-media thickness, and measured flow-mediated dilation of the brachial arteries. The PCOS patients had a significantly greater mean intima-media thickness compared with controls (0.53 mm versus 0.39 mm). They also...
- Cortisol dips in PCOS patients treated for sleep apnea: study.(Gynecology)
- Magazine article from: OB GYN News Bates, Betsy October 1, 2005 700+ words
...levels at night as well as during the daytime. Obstructive sleep apnea symptoms also greatly improved in five nondiabetic PCOS patients who received continuous positive airway pressure (CPAP) for 8 weeks as part of a study presented at the annual meeting...
- Early heart disease in PCOS patients.(Clinical Capsules)(Polycystic ovary...
- Magazine article from: Family Practice News December 1, 2004 700+ words
...s carotid arteries to gauge intima-media thickness, and measured flow-mediated dilation of the brachial arteries. PCOS patients had a significantly greater mean intima-media thickness compared with controls (0.53 mm versus 0.39 mm) as well as...
Source: HighBeam Research, Metformin May Be Useful For PCOS Patients With Metabolic Syndrome...