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Exercise, HRT Independently Reduce Fat Mass And Improve Insulin Action.(hormone replacement therapy)
2001 AUG 9 - (NewsRx Network) -- by N.R. Saltmarsh, staff medical writer Postmenopausal women who exercise and take hormone replacement therapy (HRT) have less fat mass and better insulin action, say researchers working in the United States.
HRT and exercise each appear to act independently and to enhance the effect of the other, noted E.M. Evans and colleagues, Washington University, St. Louis, Missouri, and University of Colorado, Denver, who proposed that HRT may influence insulin action by changing central fat.
Evans and team studied the individual and combined effects of exercise (two months of flexibility training followed by nine months of endurance training) and HRT in postmenopausal women assigned to control (n=19), exercise (n=18), HRT (n=15), and exercise + HRT (n=16) groups.
Exercise significantly reduced fat overall and in the trunk, arms, and legs and improved glucose tolerance and insulin action, reported Evans and coworkers. HRT also showed significant main effects on the reduction of total fat mass (HRT, -3.0 [+ or -] 4.0 kg; no HRT, -1.3 [+ or 2.6 kg), with a strong trend for reductions in trunk and leg fat mass and significantly improved insulin action, they added ("Effects of HRT and exercise training on insulin action, glucose tolerance, and body ...
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