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Preclinical Data Are Promising On Chlamydia Vaccine.(Brief Article)
2001 AUG 22 - (NewsRx.com & NewsRx.net) --
Antex Biologics, Inc. (ANX) announced that immunization with its new, proprietary Chlamydia trachomatis vaccine demonstrated protection against infertility in animals.
In preclinical studies, mice challenged with live C. trachomatis bacteria were immunized with the vaccine. In a significant number of mice, the infection cleared and they were protected against infertility. Ninety percent of those not immunized became infertile.
These results, in concert with other preclinical studies involving Antex C. trachomatis proteins, suggest that the development of a safe and effective vaccine to prevent acute C. trachomatis infections and complications is within sight. Clinical trials begin next year.
"Chlamydia trachomatis is one of the most significant bacteria that causes sexually transmitted diseases," said Stephen N. Keith, MD, MSPH, Antex. "A vaccine to prevent this infection and its complications will represent a major breakthrough in clinical practice and public health, and we're thrilled that Antex is leading that effort."
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