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Antibody's Crystal Structure Could Yield Design Clues.(Brief Article)
2001 AUG 22 - (NewsRx.com & NewsRx.net) --
A team of scientists has revealed the crystal structure of the human antibody b12 for a protein on HIV-1's viral envelope called gp120, which aids HIV's entrance into a cell by binding to CD4 receptors on the cell's surface.
Erica Ollmann Saphire, Scripps Research Institute in La Jolla, California, and colleagues reported their findings in the journal Science.
b12 is only one of three isolated human antibodies that are potent enough to neutralize the HIV-1 virus in living animals and in the lab, so researchers hope to glean clues from its structure that will allow them to design ...
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Source: HighBeam Research, Antibody's Crystal Structure Could Yield Design Clues.(Brief Article)