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Fitzmaurice DA, Hobbs FD, Murray ET, et al. Oral anticoagulation management in primary care with the use of computerized decision support and near-patient testing: a randomized, controlled trial Arch Intern Med 2000 Aug 60:2343-8.
QUESTION: For patients who require oral anticoagulation, is a nurse led clinic that uses onsite blood testing and a computerised decision support system as effective as routine hospital care for maintaining appropriate international normalised ratios (INRs)?
Design
Randomised {allocation concealed}*, unblinded, controlled trial with 1 year of follow up.
Setting
9 of 21 potential general practices in Birmingham, UK.
Patients
224 adults (55% men) who were receiving warfarin. Follow up was 82%.
Intervention
122 patients were allocated to nurse …