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Aggressive Treatment For Cardiovascular Disease: Helpful Or Not For Women?
2001 JUL 26 - (NewsRx Network) -- Women with cardiovascular disease often receive less aggressive treatment, but a study published in the July 2001 issue of the Journal of the American College of Cardiology suggests that this may be an instance of "no harm, no foul."
It concluded that aggressive treatment helps men with unstable coronary artery disease, but not women.
The study's results, however, which are based on subset analysis, may be questionable.
"In contrast to its beneficial effect in men, an early invasive strategy did not reduce the risk of future events among women," wrote Dr. Bo Lagerqvist, of the University Hospital in Uppsala, Sweden, and colleagues. "Further research is warranted to identify the most appropriate treatment strategy in women with unstable coronary artery disease."
Lagerqvist and team analyzed data from a study called the Fragmin and fast Revascularization during InStability in Coronary artery disease (FRISC II) trial. Designed to compare treatment strategies, FRISC II randomly assigned 749 women and 1,708 patients with unstable coronary artery disease to receive either invasive or noninvasive treatment. The study found that patients who underwent angiography and an invasive procedure to restore blood flow in blocked arteries did better than those treated more conservatively.
But Lagerqvist and his colleagues found important gender differences ...
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