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2001 JUL 26 - (NewsRx Network) -- by Sonia Nichols, senior medical writer - A study of hepatitis C virus (HCV) infections among children in Italy during the last decade has revealed almost half of the youngsters acquired HCV from their mothers.
Injecting illegal drugs, undergoing blood transfusions, and having unprotected sexual contact with an infected individual are some of the risk factors for becoming infecting with HCV. However, mothers infected with HCV can pass the virus to their infants during pregnancy, a process known as vertical transmission. Medical researchers in Italy say vertical transmission caused as many as 46% of pediatric HCV cases in the past decade, with blood transfusions making up another third of pediatric infections.
F. Bortolotti and colleagues, representing the University Federico II and other Italian medical centers, conducted a review of 606 children identified with HCV between 1990 and 1999. The review consisted of information gathered from medical records and an anonymous questionnaire.
"Maternal infection (46% of cases) and blood transfusions (34%) were the most frequent risk factors," Bortolotti and coworkers said.
Two-hundred seventy-nine of the mothers were infected with HCV. Although a majority of the women did not know how they may have become infected, one-third of them ...