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Differences In Visceral Fat Account For Heart Risk Discrepancies.(between white women and black women in South Africa)

Women's Health Weekly

| July 26, 2001 | Saltmarsh, N.R. | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 JUL 26 - (NewsRx Network) -- by N.R. Saltmarsh, staff medical writer -Visceral fat may be the culprit behind the tendency of white women to have higher rates of ischemic heart disease than black women in South Africa.

C. Punyadeera and associates at the University of Witwatersrand looked for biochemical explanations for this difference among 15 obese black women (OBW) and 14 obese white women (OWW), all premenopausal, who submitted to an overnight fast and testing for blood concentrations of glucose, nonesterified fatty acids (NEFAs), catecholamines, plasminogen activator inhibitor-1, C-peptide, pro-insulin, lipograms, cortisol, growth hormone, and post-heparin lipoprotein.

Body composition measurements revealed that visceral fat area was higher in OWW (139.7 [+ or -] 10.7 [cm.sup.2]) than in OBW (72.3 [+ or -] 3.9 [cm.sup.2]). The OWW also had higher fasting and three-hour triglyceride concentrations, higher NEFA levels at three and four hours, and higher fasting cortisol (266 [+ or -]24 vs. 197 [+ or -] 19 nmol/I) than OBW ("Ethnic differences in lipid metabolism in two groups of obese South African women," Journal of Lipid Research, 2001;42(5):760-767).

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