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Older Women At Greater Risk If They Have High Bone Density.(breast cancer)
2001 JUL 12 - (NewsRx Network) -- Investigators have found that older women with high bone-mineral density (BMD) are nearly three times as likely to develop breast cancer as are older women with low BMD, and that their tumors tend to be at an advanced stage at diagnosis.
Results of the study were published in the June 20, 2001, issue of the Journal of the National Cancer institute and confirm a smaller University of Pittsburgh study published in the Journal of the American Medical Association in 1996.
"This study shows that there is an inverse relationship between osteoporosis and invasive breast cancer, two of the most common and important conditions affecting an older woman's health," said Jane Cauley, DPH, associate professor of epidemiology, University of Pittsburgh Graduate School of Public Health, Pennsylvania, and study co-author. "The results suggest that bone mineral density is one of the most powerful predictors of breast cancer, especially advanced breast cancer, among elderly women."
Investigators stressed than high BMD itself is not the cause of breast cancer, but a marker for hormone levels, and that women should not discontinue their efforts to maintain bone mass through diet or medication.
"Sex steroid hormones, like testosterone and estrogen, or other growth promoting hormones, may be the link to breast cancer," said Cauley, "and BMD may reflect a woman's long-term exposure to these hormones. Further studies are needed to identify the common denominator."
At the start of the study, ...
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Source: HighBeam Research, Older Women At Greater Risk If They Have High Bone Density.(breast...