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Researchers Examine Feasibility Of Wheat-Based Edible Vaccine.(Brief Article)

Vaccine Weekly

| August 08, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 AUG 8 - (NewsRx.com & NewsRx.net) --

Could vaccines ever be as simple and easy to receive as eating a piece of bread?

Two biology professors at the University of North Carolina at Charlotte believe it might be possible and are working to learn if wheat can be a means to administer vaccines for humans and animals.

Professors Thomas L. Reynolds and Kenneth L. Bost have received research funding from the North Carolina Biotechnology Center to determine if wheat can be grown with specific DNA that can help people and animals develop immunity to diseases. The biotechnology center awarded Reynolds and Bost $55,000 to conduct research over an 18-month period. The Foundation for the Carolinas also is funding the study.

The research project brings together researchers from two vastly different fields. Reynolds' area of research expertise is plant molecular biology/biotechnology. He has published extensively in the field and in 1999 became a consultant for the Food and Agriculture Organization, an agency of the United Nations. Bost is an internationally known immunologist. He studies the immune system and how it works to protect the body from pathogens, such as bacteria, viruses, and infectious diseases.

The research project will begin in Bost's laboratory, where he is studying a particular herpesvirus that can cause a mononucleosis-like disease. Bost has been able to isolate individual genes of the virus in an effort to determine whether the proteins encoded by these genes might serve as vaccines.

Reynolds will take a specific gene of the herpesvirus and try to inject it into wheat seed. The key will be getting the viral DNA to become part of the chromosomal DNA of the wheat. If successful, he then will use ...

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Source: HighBeam Research, Researchers Examine Feasibility Of Wheat-Based Edible Vaccine.(Brief...

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