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Data Reported From Comparison Study.(medications for the treatment of urinary incontinence)
2001 JUL 5 -- (NewsRx Network) -- In a trial to compare medications for the treatment of overactive bladder, Ditropan XL (extended-release oxybutynin chloride; Alza Corp.) showed a significant advantage over Detrol [R] (tolterodine tartrate Pharmacia).
Peter Sand. MD. presented results from the OBJECT Study at the recent meeting of the American College of Obstetricians and Gynecologists in Chicago. Illinois, (OBJECT -- Overactive Bladder: Judging Effective Control and Treatment). Sand is director of the Evanston Continence Center in Evanston. Illinois.
The trial was designed to compare the two most commonly used drugs prescribed for urge urinary incontinence. Urge incontinence is characterized by a sudden feeling of impending voiding, often followed by wetting oneself.
The 378 study subjects, about 80% women, kept a diary of how frequently they had to urinate and the number of episodes of incontinence they experienced. They then received either Ditropan XL once a day in the morning or Detrol twice a day. At the end of 12 weeks of treatment, patients receiving either medication had significantly fewer urge incontinence episodes, total incontinence episodes. or frequency of needing to urinate, compared with before treatment. However, the study showed that Ditropan XL was the more effective medication of the two.
"There were significantly fewer urge incontinence episodes and total incontinence episodes, and urinary frequency or voiding episodes ...
- Drug Decreases Incontinence Episodes by 83%.(Ditropan XL)(Brief Article)
- Magazine article from: Family Practice News BRUNK, DOUG March 15, 2000 700+ words
SAN DIEGO -- Ditropan XL decreases the number of incontinence episodes per week by about 83...involved 419 patients on Ditropan XL (oxybutynin chloride...reduction in urinary incontinence episodes per week. The reduction...
- Ditropan XL Is Significant Advancement in Treatment of Urinary Incontinence.
- Press release article from: PR Newswire May 16, 2001 700+ words
...study showed that Ditropan XL was the more effective...significantly fewer urge incontinence episodes, total incontinence...people taking Ditropan XL and 31% more total incontinence episodes in the Detrol group compared to Ditropan XL." Side ...
- Ditropan XL a Significant Advance in Treating Urge Incontinence; New Delivery...
- Press release article from: PR Newswire July 17, 2001 700+ words
...number of incontinence episodes. However, Ditropan XL was significantly...them women, Ditropan XL was 28...number of urge incontinence episodes, 31% better...reducing total incontinence episodes, and reduced...10 mg of Ditropan XL once a ...
- PRESS RELEASE: Ditropan XL is significant advancement in treatment of urinary...
- News wire article from: Chemical Business Newsbase May 23, 2001 700+ words
...They then received either Ditropan XL once a day in the morning...significantly fewer urge incontinence episodes, total incontinence episodes, or frequency of needing...the study showed that Ditropan XL was the more effective...
- ALZA's Ditropan XL Approved for Treatment of Overactive Bladder.
- Press release article from: PR Newswire December 17, 1998 700+ words
...a statistically significant reduction in urge urinary incontinence episodes, with a low dropout rate due to side effects," said...Ditropan(R) XL experienced between 15 to 18 fewer urge incontinence episodes per week. In clinical trials, Ditropan(R) XL was...
- ALZA ANNOUNCES UNITED KINGDOM APPROVAL OF ONCE-DAILY DITROPAN XL.
- Press release article from: PR Newswire June 19, 2000 700+ words
...patients treated with Ditropan(R) XL reported an 83 per cent - 90 percent reduction in their mean weekly urge incontinence episodes. Ditropan(R) XL was demonstrated to be generally well tolerated in patients. The most common side effects...
- ALZA Announces Expansion of Ditropan XL(R) Promotion to Primary Care Audience...
- Press release article from: PR Newswire January 9, 2001 700+ words
...as part of its promotional efforts on Ditropan XL(R). Under the agreement, UCB Pharma...sales force currently co-promoting Ditropan XL(R), the total number of primary...professionals dedicated to promoting Ditropan XL(R) will increase to more than 1...
- Impax receives final FDA approval and first-to-file status for generic version...
- News wire article from: Chemical Business Newsbase November 10, 2006 700+ words
...ANDA) for a generic version of Ditropan XL, Extended-release Tablets, 15...product. Alza Pharmaceuticals markets Ditropan XL for the treatment of urge urinary incontinence. US sales of Ditropan XL 15 mg were about $58 M in the 12...
- ALZA Corporation to Appeal U.S. District Court Decision on DITROPAN XL(R)...
- Press release article from: PR Newswire September 28, 2005 700+ words
...District Court decision that a patent on DITROPAN XL(R) (oxybutynin chloride) extended...West Virginia, held that the patent on DITROPAN XL is invalid and that Mylan Laboratories...McNeil Pharmaceutical, Inc. markets DITROPAN XL in the U.S. and ALZA Corporation...
- Impax comments on Alza's lawsuit related to generic version of Ditropan XL.
- News wire article from: Asia Africa Intelligence Wire September 9, 2003 700+ words
...Application (ANDA) for a generic version of Ditropan XL (oxybutynin chloride) Tablets, 15 mg. Ditropan XL Tablets are used for the treatment of...According to NDCHealth, US sales of Ditropan XL Tablets, 15 mg were $45 M for the 12...
Source: HighBeam Research, Data Reported From Comparison Study.(medications for the treatment of...