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Japanese Knotweed Derivative Prevents Cancer Growth, Spread In Mice.(lung cancer treatment)
2001 JUN 28 - (NewsRx Network) -- by Sonia Nichols, senior medical writer - The roots of Japanese knotweed, a bamboo-like perennial, produce a compound that may be valuable for fighting lung cancer.
Researchers at Ehime University School of Medicine in Japan have isolated resveratrol from the roots of Polygonum cuspidatum and determined that it blocks blood vessel formation and cancer spread in mouse lung cancer tumors. Resveratrol, commonly consumed in red wine, is also isolated from parts of other plants such as muscadines, peanuts, and eucalyptus and may have cardioprotective. antioxidant, anticancer, and phytoestrogenic properties.
"We found that resveratrol, at doses of 2.5 and 10 mg/kg, significantly reduced the tumor volume (42%), tumor weight (44%), and metastasis to the lung (56%) in mice bearing highly metastatic Lewis lung carcinoma (LLC) tumors, but not at a dose of 0.6 mg/kg," reported Yoshiyuki Kimura and colleagues.
Preliminary analysis showed that resveratrol prohibited DNA activity in LLC tumor cells.
Kimura's group also found that in mice, resveratrol inhibited the formation of new tumor blood vessels, and they concluded resveratrol does not influence cells of the immune response system as a means of producing anticancer activity ("Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and ...
- Japanese Knotweed Derivative Prevents Cancer Growth, Spread In Mice.(Brief...
- Newspaper article from: Cancer Weekly June 26, 2001 700+ words
...The roots of Japanese knotweed, a bamboo...for fighting lung cancer. Researchers...search term "lung cancer therapy" yielded...include: * Japanese knotweed-derived resveratrol...mice bearing lung cancer tumors * Resveratrol...
- Biological warfare vow to kill Japanese knotweed.(News)
- Newspaper article from: Western Mail (Cardiff, Wales) December 7, 2004 700+ words
...biological warfare will begin on dreaded Japanese knotweed in Wales. The agent in this case...but an innocent-looking fungus. Japanese knotweed has plagued hedgerows, verges...promising organisms which could attack Japanese knotweed in Wales without going on to devastate...
- New Advice On A Horticultural Invader.(managing Japanese knotweed...
- News wire article from: Mondaq Business Briefing August 8, 2007 700+ words
...Originally published in Estates Gazette Japanese knotweed can create havoc for developers...indicated that the cost of dealing with Japanese knotweed on the Olympic site in east London...Japan, Taiwan and northern China, Japanese knotweed is a highly invasive weed. It was...
- Bug quandary over Japanese knotweed; nature watch.
- Newspaper article from: The Birmingham Post (England) August 7, 2009 700+ words
...tackle the introduced and troublesome Japanese knotweed (also known as 'smartweed') by...In this country we worry about Japanese knotweed, Himalayan balsam and grey squirrels...plants here) are causing concern. Japanese knotweed is one of about 1,000 species in...
- GREEDY JAPANESE KNOTWEED TAKES OVER A PLOT WITH EASE.(Lifestyle)
- Newspaper article from: Seattle Post-Intelligencer (Seattle, WA) May 2, 1996 700+ words
...the ubiquitous roadside weed called Japanese knotweed or Japanese bamboo. Oh dear. Though...plants can exceed 8 feet in height. Japanese knotweed is especially attractive when seen...wandering roots is no small feat. Japanese knotweed will sneak out of pots through the...
- UK to introduce alien species to fight Japanese knotweed.
- News wire article from: PTI - The Press Trust of India Ltd. May 6, 2008 700+ words
...introduce alien species to fight Japanese knotweed London, May 6 (PTI) -- Scientists...deal with the devastating effect of Japanese knotweed in the countryside. The authorities...ordinary methods, such as pesticide. "Japanese knotweed has been described as having the...
- Japanese knotweed.(Brief article)
- Magazine article from: New York State Conservationist October 1, 2009 700+ words
...brought this shrub here in the 1880s intended, we might love Japanese knotweed for its green foliage and August-blooming flowers. Instead...crowds out native plants. To control its spread, remove Japanese knotweed when you find it in the wild and don't use it in gardens...
- JAPANESE KNOTWEED
- Newspaper article from: The Northern Echo Tony Kelly, Crook, Co Durham. September 8, 2009 700+ words
...attracted its fair share of controversy (though as far as I know it's not poisonous), and is in flower at the moment, is Japanese knotweed. A tall, herbaceous plant with reddish stems, heartshaped leaves and sprays of little white flowers, it has the well...
