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Chlamydia pneumoniae May Play Role In Pathogenesis.(of interstitial cystitis)
2001 JUN 28 - (NewsRx Network) -- Researchers at Vanderbilt University Medical Center, Nashville, Tennessee, have discovered a potential role of Chlamydia pneumoniae in the pathogenesis of interstitial cystitis (IC).
Interstitial cystitis is a syndrome characterized by urinary frequency, urgency, nocturia, and pain with bladder filling. Some patients have significant bladder inflammation, and a few have ulcers, scarring, and stiffening. Diagnosis is based on symptoms, findings on cystoscopy and biopsy, and elimination of other treatable causes, such as infection. Because doctors do not know what causes IC, treatments are aimed at relieving symptoms.
The C. pneumoniae organism, first described in 1988, is an airborne organism transmitted via cough. As an obligate intracellular parasite, it is difficult to detect by routine cultures, can cause chronic infections, and may not elicit an acute inflammatory response. C. pneumoniae is commonly associated with respiratory tract infection, but has also been implicated in the development of coronary artery plaques.
The data, using polymerase chain reaction (PCR) analysis of urine, revealed that 81% of patients with IC and 16% of controls were positive for C. pneumoniae, suggesting a potential role for this organism in the development of IC.
Seventeen patients with IC as outlined by NIADDK criteria and six control patients underwent bladder biopsy. Selection of ...
- IC prevalence increasing.(interstitial cystitis)(Author Abstract)
- Magazine article from: Urologic Nursing Quallich, Susanne A. August 1, 2003 700+ words
...Increased prevalence of interstitial cystitis: Previously unrecognized urologic...Urology, 60(4),573-578. Interstitial cystitis (IC) is a constellation of symptoms...as an adjunct in diagnosing IC, but these authors contend...
- New concepts emerge for treatment of IC.(interstitial cystitis )
- Magazine article from: OB GYN News Finn, Robert October 1, 2005 700+ words
...Highly effective treatments for interstitial cystitis remain elusive, but new concepts...Here is a rundown of some interstitial cystitis (IC) treatment concepts she presented...eye and may be developed for IC. Montelukast, a leukotriene...
- Second indication for Plethora's IC drug PSD597.(interstitial cystitis...
- Newspaper article from: Pharma Marketletter February 12, 2007 700+ words
...development for the treatment of interstitial cystitis and painful bladder syndrome...following positive feedback from IC patients involved in the existing...efficacy in the treatment of interstitial cystitis, a chronic syndrome characterized...
- October 31 is National Interstitial Cystitis (IC) Awareness Day.
- Press release article from: PR Newswire October 31, 2007 700+ words
First Survey of IC Patients Reveals Frustration Associated...In observance of the first National Interstitial Cystitis (IC) Awareness Day, the National Association...the results of the first survey of IC patients highlighting their frustration...
- Abuse more common in women with IC: it may lead to tension in the pelvic area,...
- Magazine article from: Renal & Urology News Schieszer, John July 1, 2006 700+ words
WOMEN WITH interstitial cystitis (IC), especially those with levator pain...to investigators. Of 206 women with IC, 36.9% reported being physically...Additionally, of the women with both IC and levator pain, 55% reported abuse...
- Research from Seoul National University, Medical Department broadens...
- Magazine article from: Women's Health Weekly July 2, 2009 700+ words
...the urodynam.ic results in patients...bladder syndrome/interstitial cystitis and in those with...bladder syndrome/interstitial cystitis and 78 female...bladder syndrome/interstitial cystitis or overactive...
- Caring for the patient with interstitial cystitis.
- Magazine article from: MedSurg Nursing Kaufman, Melissa W. All, Anita C. Hall, Nita Clark, Joseph Y. August 1, 1997 700+ words
Interstitial cystitis (IC), or urethral...the presenting IC cases (Mellon, 1993). Interstitial cystitis affects every...individual with IC is included to...Historic Overview Interstitial cystitis is defined as...
- Interstitial cystitis.(Pamphlet)
- Newspaper article from: Pamphlet by: National Institute of Diabetes & Digestive & Kidney Diseases August 1, 1994 700+ words
...advancing our knowledge of interstitial cystitis, but the disorder still...debilitating disorder. Interstitial Cystitis: A Bladder Disorder The...bladder wall. People with interstitial cystitis (IC) have an inflamed, or...
