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Study Shows Transmission Of Resistant HIV Strains From Mother To Child.

Women's Health Weekly

| June 21, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 JUN 21 - (NewsRx Network) -- ViroLogic, Inc. (VLGC) has published a new study that documents the transmission of multi-drug-resistant HIV from mother to child.

According to the researchers, the study findings, which were published in the Journal of Infectious Diseases, support use of drug-resistance testing for HIV infected pregnant women who have had prior antiretroviral (ARV) therapy.

Using PhenoSense HIV, ViroLogic's phenotypic drug-resistance test, researchers identified resistance to ARV drugs (protease inhibitors and reverse transcriptase inhibitors) in virus taken from both the mother and infant, and concluded that multi-drug-resistant HIV had been passed from mother to child, despite use of a standardized drug regimen intended to prevent HEY transmission.

"This study indicates that by identifying drug resistance in an HIV positive mother and appropriately using that information, physicians can help design treatment regimens that may decrease the likelihood that she will transmit HIV to her infant during childbirth," said lead investigator Victoria Johnson, MD, of the University of Alabama at Birmingham (UAB) School of Medicine and the UAB Center for AIDS Research. "The knowledge provided ...

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Source: HighBeam Research, Study Shows Transmission Of Resistant HIV Strains From Mother To...

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