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2001 JUL 11 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Polysaccharide vaccination against serogroup C Neisseria meningitidis may be cost effective under certain conditions, but public health policy makers should consider more than cost when deciding who gets the vaccine.
That is the opinion of S. Skull and colleagues at the Royal Melbourne Hospital, who urged Australian authorities to consider noneconomic factors when deciding whether to implement large-scale meningococcal vaccination programs.
"Disease due to serogroup C N. meningitidis is life-threatening and potentially preventable by vaccination," they pointed out. "In 1999, the U.K. instigated mass vaccination after a sustained increase in serogroup C meningococcal disease. In the same year, Victoria, Australia, experienced a similar change in disease epidemiology. It is timely to undertake an economic evaluation of options for community vaccination in Australia based on local data."
The researchers evaluated the cost effectiveness of three options for delivery of polysaccharide vaccine for a hypothetical population of 15- to 19 year olds, assuming one year of program implementation and five years of vaccine protection. Life-years saved, disability-adjusted life-years (DALY) averted, cases averted, and number of people vaccinated were among the outcomes studied.
The most cost-effective option would be to vaccinate the population with a high rate of disease and the cutoff incidence for cost effectiveness - excluding direct cost savings - was 14/100,000, reported Skull and coworkers.
"Compared with no vaccination and assuming five years' duration of protection and exclusion of direct cost savings, this resulted in a discounted cost per life-year saved of $23,623, ...
Source: HighBeam Research, Community Vaccination Can Be Cost Effective.(Brief Article)