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Vaccine Generates Potent Immune Response.(Brief Article)
2001 JUL 4 - (NewsRx.com & NewsRx.net) --
Progenics Pharmaceuticals, Inc. (Nasdaq:PGNX) and Cytogen Corporation (Nasdaq:CYTO) announced that in preclinical studies their experimental prostate cancer vaccine generated a potent dual-immune response against prostate-specific membrane antigen (PSMA), a well-recognized marker found on prostate cancer cells.
The new PSMA-based therapeutic vaccine, which employs the body's own defense mechanisms to identify and destroy prostate cancer cells, yielded both antibodies and killer T cells, the two principal mechanisms used by the immune system to eliminate harmful cells. The findings were presented at the 37th annual meeting of The American Society of Clinical Oncology in San Francisco, California.
"T-cell- and antibody-based immunity represent two major arms of the human immune system," said William C. Olson, PhD, Progenics. "PSMA is an attractive target for vaccine therapy, because it is abundantly expressed on prostate cancer cells. This vaccine may provide a powerful way to train the body's natural defenses to protect against the recurrence of this deadly disease. Importantly, PSMA-based immunotherapy is designed to destroy ...
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