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2001 JUN 14 - (NewsRx Network) -- by Sonia Nichols, senior medical writer - Patients with higher-stage primary biliary cirrhosis have the same risk for developing primary liver cancer as do patients with hepatitis C virus (HCV)-related cirrhosis.
The overall risk for liver cancer in patients with primary biliary cirrhosis is lower, however, researchers at the University of Barcelona in Spain report.
Primary biliary cirrhosis (PBC) is a liver disease that primarily affects women. To assess the prevalence of liver cancer, or hepatocellular carcinoma (HCC), in a population of patients with PBC, L. Cabelleria and associates selected five men and 135 women in various stages of the disease for analysis.
"The incidence of HCC in the 45 patients with late stages of the disease (III or IV) was 11.1%, similar to that found in patients with HCV related cirrhosis," reported Cabelleria and colleagues after detecting HCC in five of the patients.
Relative risk for primary liver cancer in later stage PBC and HCV-related cirrhosis patients was almost the same ("Hepatocellular carcinoma in primary biliary cirrhosis: Similar incidence to that in hepatitis C ...