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2001 JUN 14 - (NewsRx Network) -- Matritech, Inc. (NMPS) announced that it has begun patient recruitment for a multicenter clinical study of its NMP66 blood test for the early detection of breast cancer.
The clinical study, which will be conducted at six medical centers around the U.S., will enroll approximately 1,000 patients. It will include about 700 women with lesions that are either visible on mammogram or palpable, and who have been recommended by their physicians to have a further diagnostic procedure such as biopsy. An additional 300 women with normal mammograms will also be recruited.
The trial will investigate the ability of the NMP66 blood test to detect cancer, differentiate between benign and malignant lesions, and identify patients with normal mammograms. The goal of the study is to investigate the NMP66 blood test as a potential screening procedure for breast cancer.
"The key to fighting and treating breast cancer is early detection," said David L. Corbet, Matritech. "According to the American Cancer Society, five-year survival for women in whom the disease is detected at its earliest stage is greater than 96%. However, survival for this length of time decreases to 21% in women with late-stage, metastatic disease."
"Despite the encouraging progress that the medical community has made in detecting breast cancer, only 62% of breast cancers diagnosed between 1989 and 1995 were found while still localized," added Corbet. "While mammography is still the best detection method, the number of false positives is high. Clearly, there is a need for a blood-based screening tool to enhance existing methods of detecting breast cancer, and NMP66 has the potential to fulfill this role."
"This is the type of test my patients have been hoping to use for over 20 years," said Avi BenOra, MD, a radiologist and former president of the Arizona division of the American Cancer Society. "Because almost half the women in the U.S. who should be getting annual mammograms are not, there is a critical need ...
Source: HighBeam Research, Recruitment For Clinical Study Of Screening Test Begins.(NMP66 blood...