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New Low-Dose Formulations As Effective, Possibly Safer Than Commonly Prescribed Doses.(hormone replacement therapy )
2001 JUN 14 (NewsRx Network) -- Two articles in the June 2001 issue of Fertility and Sterility show that new lower dose forms of hormone replacement therapy (HRT) for menopausal women are just as effective as commonly prescribed doses.
The articles both stem from the Women's Health, Osteoporosis, Progestin, Estrogen (Women's HOPE) study, a two-year clinical trial of the safety and efficacy of lower-dose regimens of HRT in postmenopausal women. The Women's Hope project involved more than 2,600 women at multiple sites and was supported by Wyeth-Ayerst Research.
The first article compares patients (postmenopausal women age 40-65) on different doses of estrogen and progesterone. Participants were randomly assigned into one of eight groups and given different doses of the hormones, or a placebo. The frequency and intensity of hot flashes were compared, as was vaginal atrophy (Utian et al., "Relief of vasomotor symptoms and vaginal atrophy with lower doses of conjugated equine estrogens and medroxyprogesterone acetate," Fertil Steril, June 2001;75(6)).
The investigators concluded that lower doses of the hormones, ...
- Commonly prescribed drug causes osteoporosis. (thyroid hormones)
- Newspaper article from: HealthFacts July 1, 1988 700+ words
COMMONLY PRESCRIBED DRUG CAUSES OSTEOPOROSIS Long-term use of commonly prescribed thyroid hormones has been shown to cause bone loss in premenopausal women. Thirty-one women, aged 19 to 46, who had been on thyroid hormone replacement therapy...
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- Psychiatric manifestations of medications commonly prescribed in otolaryngology.
- Magazine article from: Ear, Nose and Throat Journal Levy, Steven Abaza, Mona M. Hawkshaw, Mary J. Sataloff, Robert T. April 1, 2001 700+ words
...psychological professionals should be familiar with the potential psychiatric side effects of medications that are commonly prescribed by otolaryngologists. Because some of these side effects are atypical, their relationship to medications might...
- Feds to begin clinical tests on drugs commonly prescribed for children.
- Newspaper article from: Medical Letter on the CDC & FDA February 16, 2003 700+ words
...amp; NewsRx.net) -- The U.S. government has announced plans to begin clinical tests in 2003 on 12 drugs commonly prescribed for children even though their safety and effectiveness has been tested only in adults. "Children often react...
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- News wire article from: Asia Africa Intelligence Wire September 30, 2002 700+ words
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- News wire article from: Asia Africa Intelligence Wire September 27, 2002 700+ words
...caused by Streptococcus pneumoniae taken once daily for five to 10 days was as active as clarithromycin, a commonly prescribed macrolide, taken twice daily for 10 days, according to data presented at the 42nd annual Interscience Conference...
Source: HighBeam Research, New Low-Dose Formulations As Effective, Possibly Safer Than Commonly...