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2001 JUN 14 - (NewsRx Network) -- HIV-1 infected mothers in less-developed countries who breastfeed their infants could be more than three times more likely to die within two years of giving birth compared with mothers who use formula milk, say pediatricians in the May 26, 2001, issue of the Lancet.
Their study also found that illness and death was increased among children of HIV-1 infected breastfeeding mothers.
Ruth Nduati and colleagues from the University of Nairobi, Kenya, and the University of Washington, Seattle, USA, analyzed data from a previous trial, which had investigated mother-to-child HIV-1 transmission from breastmilk, to examine the effect of breastfeeding on maternal death rates in the first two years after childbirth.
Pregnant women attending four city council clinics in Nairobi, Kenya, were offered HIV tests. At about 32 weeks' pregnancy, 425 HIV-1 seropositive women were randomly allocated to either breastfeed or formula feed their infants. After delivery, mother-infant pairs were followed up monthly during the first year and quarterly during the second year until death, or for two years after delivery, or until the end of the study.
Death among mothers was higher in the breastfeeding group than in the formula group (18 deaths in ...