AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Blood Cell Stimulant May Direct Pathogenesis.(erythropoietin levels may influence the development of endometriosis)
2001 JUN 7 - (NewsRx Network) -- by Sonia Nichols, senior medical writer - A protein that stimulates the formation of red blood cells may also influence the development of endometriosis in females, new research suggests.
Sachiko Matsuzaki and coworkers at Tohoku University School of Medicine in Japan have found women with endometriosis have greater levels of the protein erythropoietin in their peritoneal fluid as compared with women without endometriosis. Because erythropoietin may influence the early development of endometriosis, drugs designed to inhibit peritoneal erythropoietin levels could, potentially, be used for treating the initial stages of the disease.
Erythropoietin (Epo) is commonly known for its influence on erythropoiesis, the formation of new red blood cells. "However, recent studies have indicated that Epo also has angiogenic properties and plays an important role in the estrogen-dependent cyclical angiogenesis within the mouse uterus," said Matsuzaki and colleagues in the May 2001 issue of Human Reproduction.
To study comparable effects in humans, researchers tested the peritoneal fluid of 42 women with endometriosis and 18 without endometriosis for Epo concentrations.
All samples contained Epo, according to the researchers, but concentrations of Epo were higher in women with endometriosis than without endometriosis (13.1 [+ or -] 1.2 miIU/ml and 7.2 [+ or -] 0.7 mIU/ml, respectively, mean [+ or -] SE, P[less ...
- Interleukin concentrations vary in peritoneal fluid of women with endometriosis.
- Newspaper article from: Blood Weekly June 17, 2004 700+ words
...concentrations vary in the peritoneal fluid of women with endometriosis. According to...with and without endometriosis. Peritoneal fluid samples were obtained...the extension of endometriosis. The peritoneal fluid mononuclear cells...
- Peritoneal fluid has lower amounts of some proteins and increased IL-10.
- Newspaper article from: Biotech Week July 2, 2003 700+ words
...net) -- Endometriosis involves peritoneal fluid with lower...present in the peritoneal fluid. However, mild endometriosis was associated...apparent in the peritoneal fluid of patients...Severe endometriosis was also...
- Peritoneal fluid macrophages jumpstart endometrial inflammation.
- Newspaper article from: Genomics & Genetics Weekly April 23, 2004 700+ words
...NewsRx.net) -- Peritoneal fluid macrophages jumpstart...United States, "peritoneal fluid macrophages (PFM...activated in women with endometriosis, in whom they are...of Gynecology and Endometriosis. This article was...
- Molecular abnormalities exist in the peritoneal fluid of ovarian cancer...
- Newspaper article from: Cancer Vaccine Week September 15, 2003 700+ words
...Molecular abnormalities exist in the peritoneal fluid of ovarian cancer patients. "To...be used to detect cancer cells in peritoneal fluid, we tested 14 ovarian cancers and...primary tumor, normal tissue, and peritoneal fluid were analyzed. The highest frequency...
- Detected peritoneal fluid in small bowel obstruction is associated with the...
- Magazine article from: Canadian Journal of Surgery O'Daly, Brendan J; Ridgway, Paul F; Keenan, Niamh; Sweeney, Karl J; Brophy, David P; Hill, Arnold D K; Evoy, Denis; O'Higgins, Niall J; McDermott, Enda W M June 1, 2009 700+ words
...and 30 (34%) underwent surgery. Peritoneal fluid detected on a CT scan (n = 37) was...Logistical regression identified peritoneal fluid detected on a CT scan as an independent...84). Conclusion: The presence of peritoneal fluid on a CT scan in patients with adhesional...
- VEGF Receptor Mediates Peritoneal Fluid Accumulation In Hepatic...
- Newspaper article from: Angiogenesis Weekly May 11, 2001 700+ words
...vascular endothelial growth factor (VEGF)-A modulates peritoneal fluid accumulation in primary liver cancers, the results...cancer * KDR/Flk-1 performs a prominent role in peritoneal fluid accumulation in primary liver cancer
- VEGF Receptor Mediates Peritoneal Fluid Accumulation In Hepatic Cancers.
- Newspaper article from: Hepatitis Weekly May 7, 2001 700+ words
...vascular endothelial growth factor (VEGF)-A modulates peritoneal fluid accumulation in primary liver cancers, the results of...liver cancer * KDR/Flk-1 performs a prominent role in peritoneal fluid accumulation in primary liver cancer This article was prepared...
- iPTH levels have a role in selecting magnesium concentration of peritoneal...
- Newspaper article from: Health & Medicine Week November 3, 2003 700+ words
...3 - (NewsRx.com & NewsRx.net) -- iPTH levels have a role in selecting magnesium concentration of peritoneal fluid in patients undergoing CAPD. According to recent research from Greece, "We carried out this retrospective...
