AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Reason Behind Vaccine's Lack Of Efficacy In Elderly Remains Elusive.(Brief Article)
2001 JUN 27 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - The ongoing emergence of antibacterial-resistant strains of Pneumococcus, despite approval of the 23-valent pneumococcal polysaccharide (PPS) vaccine, has renewed interest in answering a common question: Why doesn't the vaccine work better in the elderly?
"The protective efficacy of this vaccine for the growing population of adults aged >65 years remains controversial," wrote J.B. Rubins, University of Minnesota School of Medicine, and associates in Drugs and Aging. "The apparent effectiveness of pneumococcal immunization in clinical studies of elderly adults has varied depending upon whether a reduction in pneumococcal colonization, pneumonia, bacteremia, or death was used as an outcome."
These studies have found a protective efficacy from the vaccine anywhere from 56% to 81%, reported Rubins and colleagues. Its ability to augment the benefit of the influenza vaccine in preventing community-acquired pneumonia may make it especially useful for the elderly, they added.
Among the possible reasons the vaccine does not meet expectations in that population are infection with nonvaccine serotypes, inadequate antibody responses, or compromised, nonhumoral host defenses.
Future research should test evolving versions of the vaccine, including newer protein conjugates or DNA vaccines, in elderly candidates who are ...
- Minnesota school fund follows managers to new firm.(Minnesota School District...
- Magazine article from: The Bond Buyer Kaplan, David September 11, 1995 700+ words
...remain the same. The trustees of the Minnesota School District Liquid Asset Fund have decided...to run the fund, now known as the Minnesota School District Liquid Asset Fund Plus...billion in assets, including the Minnesota school fund, she said. "Basically, the...
- Minnesota school wish lists reach $540M.
- Newspaper article from: Finance and Commerce Daily Newspaper, MN September 11, 2007 700+ words
...last year, according to the Minnesota School Boards Association. Greg Abbott, a spokesman for the Minnesota School Boards Association, said higher...second-highest number since the Minnesota School Board Association began tracking...
- Minnesota. (school bond ratings)(Around the Nation)
- Magazine article from: The Bond Buyer Hattori, April August 24, 1993 700+ words
...Investors Service last week assigned its first rating to a Minnesota school district bond issue supported by the state's new credit...amp; Poor's Corp. assigned an AA rating to three Minnesota school district bond issues, including Thief River Falls. The...
- Minnesota school boards group identifies 100 potential savings: 100...
- News wire article from: The America's Intelligence Wire January 21, 2009 700+ words
...state mandates to help schools be more efficient? The Minnesota School Boards Association has 100 suggestions. Among them: Don...com to see the full list of 100 suggestions from the Minnesota School Boards Association.
- Northwest Minnesota school districts approve referendums.
- News wire article from: Grand Forks Herald (Grand Forks, ND) November 9, 2005 700+ words
...Legislature increased it this year. In the meantime, many Minnesota school districts passed operating referendums that increased local...on the vote," Church said. Here's a roundup of area Minnesota school elections. ADA-BORUP: Voters approved by 621-102...
- EPA Recognizes Two Minnesota School Districts for Improving School Air Quality.
- News wire article from: The America's Intelligence Wire December 3, 2004 700+ words
...353-8254 CHICAGO, Dec. 3 /U.S. Newswire/ -- Two Minnesota school districts -- Elk River and Mankato -- are among 12 cited...Symposium in Washington, D.C. "We congratulate these two Minnesota school districts for providing good indoor air quality for their...
- Report proposes one health plan for all Minnesota school employees.
- Magazine article from: Managed Care Weekly February 16, 2004 700+ words
...a state-appointed task force is recommending that all Minnesota school-district employees be required to join one insurance...seven union members. Joanne McCabe, a director of the Minnesota School Board Association, backed a different approach that would...
- Attorney fees available with offer of judgment.(case against Minnesota School...
- Magazine article from: Minnesota Lawyer Cohen, Mark January 20, 2003 700+ words
...Anderson. The 20-page decision is Collins, et al. v. Minnesota School of Business, Inc., Minnesota Lawyer No. SC-08-03...once and for all," he stated. Bad for business? The Minnesota School of Business (MSB) offers one- and two-year programs...
- MINNESOTA: School on the Bubble.
- Magazine article from: The Bond Buyer May 9, 2001 700+ words
...debt an underlying rating of Aa3. The credit is boosted to Aa1 by the district's participation in the more highly rated Minnesota School District Credit Enhancement Program. Standard & Poor's and Fitch rate the bonds AA-plus. Moody's analysts...
- Minnesota School Readiness Business Advisory Council (MSRBAC) Announced;...
- Press release article from: PR Newswire April 20, 2004 700+ words
...PRNewswire/ -- Al Stroucken, Chief Executive Officer of the St. Paul-based H.B. Fuller Company, will chair the Minnesota School Readiness Business Advisory Council (MSRBAC). Some 80 business leaders from more than 50 Minnesota companies have formed...
Source: HighBeam Research, Reason Behind Vaccine's Lack Of Efficacy In Elderly Remains...