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Vaccine Protects Against Array Of HIV Strains.(Brief Article)

Vaccine Weekly

| June 20, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 JUN 20 - (NewsRx.com & NewsRx.net) --

VaxGen, Inc. (VXGN) presented laboratory data at a scientific conference indicating that the company's HIV/AIDS vaccine induces immune responses capable of preventing infection from a broader array of HIV strains than previously thought.

This represents new evidence that the vaccine, AIDSVAX, may be effective against HIV strains found in nature, also known as primary isolates, or "wild type" strains, the company says. The finding was made possible by a new assay developed at VaxGen that allowed company scientists to more accurately measure how well antibodies induced by the vaccine prevented cell-to-cell transmission of the virus.

Cell-to-cell transmission, in which a diseased human cell infects healthy ones, is considered one of the major routes of spreading HIV infection. The new assay showed that antibodies induced by the vaccine bound to infected T cells. Furthermore, the antibodies prevented the diseased cells from infecting ...

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Source: HighBeam Research, Vaccine Protects Against Array Of HIV Strains.(Brief Article)

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