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Vaccine Demonstrates 18% Response In Non-Small-Cell Disease.(Brief Article)

Vaccine Weekly

| June 20, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 JUN 20 - (NewsRx.com & NewsRx.net) --

Cell Genesys, Inc. (CEGE) reported data on its GVAX(R) lung cancer vaccine that demonstrate anti-tumor activity has been observed in every cancer that the GVAX vaccine has been tested in to date.

The company is currently preparing for Phase III trials. Interim clinical data from Cell Genesys' multicenter Phase I/II GVAX lung cancer vaccine trial demonstrated objective evidence of anti-tumor activity including a major response rate of 18% in patients with advanced non-small-cell lung cancer who had failed chemotherapy and/or radiation therapy.

The interim clinical trial data, presented at the June 2001 American Society of Gene Therapy (ASGT) in Seattle, Washington, included results on 30 currently evaluable patients with advanced or early-stage lung cancer. Of 22 patients with advanced lung cancer, three patients, two of whom had failed chemotherapy and one who failed radiation therapy, showed a complete disappearance of metastatic tumors following treatment with GVAX lung cancer vaccine. One other patient who failed radiation and chemotherapy had partial (greater than 50%) reduction in tumor size.

In addition to these major responses, four patients currently have ...

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Source: HighBeam Research, Vaccine Demonstrates 18% Response In Non-Small-Cell Disease.(Brief...

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