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Increasing Vaccination Leads To Herd Immunity.(Brief Article)
2001 JUN 13 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - The increasing incidence of varicella vaccination in North Carolina day care centers has been accompanied by an even faster decline in infection, implicating a "herd effect" in this patient population.
D.A. Clements and colleagues at Duke University called the effect "significant" and said it would have long-term implications for varicella epidemiology.
The researchers conducted a five-year study of varicella incidence and vaccination rates in 11 private day-care centers and preschools in North Carolina starting in 1995, following licensure of the varicella vaccine.
They noted a huge increase in varicella vaccine coverage, from 4.4% in 1995 to 63.1% in December 1999, while the cumulative varicella incidence among unvaccinated children decreased from 16.74 cases/1,000 person-months in July 1996 to 1.53 cases/1,000 person-months in December 1999 ("Partial uptake of varicella vaccine and the epidemiological effect on varicella disease in 11 day-care centers in North Carolina," Arch Pediatr Adolesc Med, 2001;155(4):455-461).
"The decrease in varicella disease is greater ...
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