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Hospitalized Patients Should Get Flu Vaccine.(Brief Article)
2001 JUN 13 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Hospital inpatients have as much or more to gain from influenza vaccination as anyone else, yet they rarely receive the vaccine while hospitalized.
If this reluctance on the part of doctors is due to the lack of data supporting the vaccine's safety and efficacy in this group, new research published in Vaccine gives the necessary green light.
In a prospective, randomized study, B.B. Berry and colleagues at Aurora Health Care, in the U.S., compared the safety and immunogenicity of influenza vaccination in 51 hospital inpatients and 177 outpatients at two private clinics.
Serum samples collected at baseline and at three weeks postvaccination revealed that the inpatient group had a seroconversion rate (defined as a fourfold increase in hemagglutination-inhibiting antibodies) of 65% and seroprotection rate (defined as titers >=1:40) of 88%.
Immunized outpatients, by comparison, had seroconversion and protection rates of 55% and 94%, respectively ("Influenza vaccination is safe and immunogenic when administered to hospitalized patients," Vaccine May 14, 2001;19(25-26):3493-3498).
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Source: HighBeam Research, Hospitalized Patients Should Get Flu Vaccine.(Brief Article)