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Maternal Antibodies May Delay and Contain EBV In Infancy.(Brief Article)
2001 JUN 6 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - The persistence of maternal antibodies in the first months of life may explain why Epstein-Barr virus (EBV) is mild or asymptomatic in infancy.
The gradual decline in an infant's blood of antibodies from the mother appears to coincide with development of EBV, K.H. Chan and colleagues found in their analysis of Hong Kong infants.
A better understanding of EBV in infancy is needed, they emphasized, because of the disease's association with infectious mononucleosis and possibly several malignancies later in life. Vaccine development hinges on this knowledge, said Chan and team.
"This study has served to clarify the epidemiology and serology of primary EBV infection during early infancy," they noted. "The pattern of EBV serological response during infancy may be important for vaccine management.
Chan and associates evaluated EBV antibodies from 66 Hong Kong infants at birth and every four months until the age of two. They found maternal antibodies in all cord blood samples and in serum samples from eight of the infants at four months.
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Source: HighBeam Research, Maternal Antibodies May Delay and Contain EBV In Infancy.(Brief...