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Immune Response To Hepatitis A Falls In Taiwanese Population.(Brief Article)
2001 JUN 6 - (NewsRx.com & NewsRx.net) --
by Sonia Nichols, senior medical writer - The authors of a Taiwanese study say factors leading to a better standard of living in Taiwan have decreased the number of young people with immune response to hepatitis A virus (HAV), placing them at greater risk for infection during an outbreak.
Shih-Min Wang and coworkers at National Cheng Kung University performed the epidemiological study, which found serum levels of antibodies to HAV (anti-HAV) declined in children and young adults between 1992 and 1998. Anti-HAV markers in the serum are indicative of protection against HAV.
In 1998, researchers tested more than 900 males and females between the ages of four months and 63 years for serum anti-HAV. Investigators separated the study participants into 14 different groups based on their ages.
"Fifteen percent of the subjects were positive for anti-HAV antibodies, which is lower than that in 1992 (P
Wang's group noted a pattern to anti-HAV prevalence among the stratified age groups. "Prevalence of seropositive subjects decreased markedly for the
Researchers attributed this decline to improved economic conditions that have lead to a modernization of sanitation practices ("Change in hepatitis A virus seroepidemiology in southern Taiwan: A large percentage of the population lack protective antibody," J Med Virol, ...
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