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2001 MAY 24 - (NewsRx Network) -- by Michael Greer. senior medical writer - Young girls infected with HIV have an increased risk for calcium insufficiency and bone degradation, researchers in Maryland warn.
"Early diagnostic efforts and advances in multidrug therapy have considerably prolonged the survival time of children infected perinatally with HIV," according to K.O. O'Brien and colleagues at Johns Hopkins University. "Despite these advances, few studies have addressed calcium status and bone growth in HIV infected children."
After performing such a study, O'Brien et al. reported that HIV infected girls were more likely to have elevated levels of bone resorption and to suffer from calcium deficits.
The average total bone mineral content for the patients studied was 845.1 [+ or -] 279.0 g. This was 2.7 standard deviations below normal bone mineral content for girls of their age and race, the researchers said.
Levels of the vitamin D metabolite 1.25-dihydroxyvitamin D (1,25[(OH).sub.2]D) were higher than normal in 25% of patients, study data showed, while parathyroid hormone levels were elevated in 12%. Despite ...
Source: HighBeam Research, Young HIV+ Girls At Risk For Bone Damage.