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Smoking, Multiparity May Put Women At Higher Risk of Cervical Cancer.

Women's Health Weekly

| May 24, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 MAY 24 - (NewsRx Network) -- by N.R. Saltmarsh, staff medical writer - Among women infected with human papillomavirus (HPV), those who smoke and those who have had three or more pregnancies are significantly more likely to advance to high-grade squamous intraepithelial lesions (HSIL) and cervical cancer (CA), according to a study from the U.S. National Cancer Institute.

A. Hildesheim and colleagues examined the risk factors for HSIL/CA by comparing 146 HPV-positive women with HSIL/CA to 843 HPV-positive women without evidence of HSIL/CA, in a population-based cohort of more than 10,000 Costa Rican women.

Their findings were as follows:

* Risk of HSIL/CA increased with increasing number of live births

* Among women with fewer than three pregnancies, oral contraceptive use increased the risk of HSIL/CA

* Women who smoked six or more, cigarettes a day had a relative risk (RR) for HSIL/CA of 2.7 compared with nonsmokers

* Current use of barrier contraceptives was associated with a RR reduction in HSIL/CA of 0.39

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Source: HighBeam Research, Smoking, Multiparity May Put Women At Higher Risk of Cervical Cancer.

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