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2001 MAY 24 - (NewsRx Network) -- by N.R. Saltmarsh, staff medical writer - Excessive androgen production in women with polycystic ovary syndrome (PCOS) may put them at risk for another disorder - obstructive sleep apnea (OSA).
Doctors treating women with PCOS should screen for sleep apnea in the medical history, suggested R.B. Fogel and team in the United States
Androgens are thought to play a role in OSA, which is much more common in men. That means women with PCOS, which is also characterized by obesity and menstrual irregularities, may be at risk for the disorder.
To clarify this risk, Fogel and colleagues with the Brigham & Women's Hospital Sleep Disorders Program measured the apnea-hypopnea index (AHI) during overnight polysomnography in 18 women with PCOS and 18 controls matched for weight and age.
They found that women with PCOS had higher AHI than controls (22.5 [+ or -] 6 versus 6.7 [+ or -] 1) and were also more likely to suffer from symptomatic OSA syndrome (44.4% vs. 5.5%).
AHI could also be positively associated with waist-hip ratio, serum testosterone, and unbound testosterone in women with PCOS, reported Fogel and team ("Increased prevalence of obstructive sleep apnea syndrome in obese women with polycystic ovary ...
Source: HighBeam Research, Obese Women With Polycystic Ovary Syndrome At Increased Risk Of Sleep...