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High HIV Viremia Does Not Increase Cancer Risk.(cervical cancer )
2001 MAY 17 - (NewsRx Network) -- by Michael Greer, senior medical writer -- High levels of plasma HIV RNA do not necessarily predispose patients to cervical cancer although high viral loads are linked to factors that do increase the risk to patients.
"The incidence of cervical dysplasia and carcinoma is known to be increased in HIV infected women," A.T. Davis and colleagues at Grady Memorial Hospital, Atlanta, Georgia, explained in the journal Gynecologic Oncology. "In addition, there is a positive correlation between HIV viral load (VL), [CD4.sup.+] count, and opportunistic infections, as well as the incidence of various malignancies."
While compromised immune integrity was found to increase cervical cancer and/or dysplasia risks, a high viral load in and of itself was not linked to a heightened carcinoma risk, Davis and coworkers reported.
Initial results did show a significant jump in the chances of finding cervical dysplasia in patients with high plasma HIV RNA levels, they said. Low CD4 cell counts were also associated with an increased cervical dysplasia risk.
However, multivariate statistical analysis ruled out high viral loads as a significant risk factor, according to the report. After such analysis, CD4 cell counts were ...
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Source: HighBeam Research, High HIV Viremia Does Not Increase Cancer Risk.(cervical cancer )