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Depression Can Hasten HIV Progression In Women.

Women's Health Weekly

| May 10, 2001 | Greer, Michael | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 MAY 10 - (NewsRx Network) -- by Michael Greer, staff medical writer - HIV infected women who suffer from depression have more complications and lower survival rates than other infected women, epidemiologists at Yale University report.

"The impact of depression on morbidity and mortality among women with [HIV] has not been examined despite the fact that women with HIV have substantially higher rates of depression than their male counterparts," wrote J.R. Ickovics and colleagues in the Journal of the American Medical Association.

Ickovics et al. found that depression in these women was linked to significantly greater immune impairment, often leading to fatal complications. Chronic depression was significantly correlated with a more pronounced decline in CD4 cells, the immune system's primary weapon against HIV, they said. This reduction was especially severe for women who already had low baseline CD4 counts and high levels of viral RNA in their bloodstreams.

Moreover, all other factors being equal, women with chronic depression were twice as likely as non-depressed women to succumb to HIV, study data showed. Mortality rates for women with very low CD4 levels (less than 200 X [10.sup.6] cells per liter) were 54% for women with ...

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