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Higher Chickenpox Vaccination Rates Decrease Disease Even In The Unvaccinated.(Brief Article)
2001 MAY 23 - (NewsRx.com & NewsRx.net) --
With more than 60% of children being vaccinated, the "vaccine has been administered to a high enough proportion of the children in the population that incidence of varicella disease has decreased within the unvaccinated population," Dr. Dennis Clements of the Duke Children's Hospital wrote in the April 2001 issue of the Archives of Pediatrics and Adolescent Medicine. "This study shows that the varicella vaccine is extremely effective even given partial use in the population."
The study involved 4,064 children in 11 private day care centers in North Carolina between 1995 and 1999. Overall, vaccine coverage increased from 4.4% in 1995 to 63.1% in 1999. There was a significant decrease in chickenpox cases during the course of the study, dropping from 5.35 cases per 1,000 children per month in 1996 to 1.01 cases in December 1999.
Among unvaccinated children, the decrease in cases was even more significant, falling from 16.74 cases per month in 1996 to 1.53 cases in 1999. This is referred to as "herd immunity," in which there are overall lower rates of disease in a community due to an increased rate of vaccination.
"Disease in children younger than one year old, who are not eligible for vaccination, virtually disappeared," Clements added.
The study was funded in part by Merck Research Laboratories Inc., Pennsylvania. Merck & Co. Inc. manufactures Varivax, the chickenpox vaccine licensed by the U.S. Food and Drug Administration in March 1995. The vaccine has been shown to prevent almost 100% of severe cases of chickenpox and more than 80% of all chickenpox.
"We used to hear about episodes where chickenpox would enter a day care center and spread right through it - classroom by classroom," Clements said. "This study shows that ...
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Source: HighBeam Research, Higher Chickenpox Vaccination Rates Decrease Disease Even In The...