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Five Vaccine Formulations Safe, Immunogenic In Humans.(Brief Article)
2001 MAY 16 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Five live, attenuated dengue vaccines are safe and well-tolerated in humans, report virologists with the U.S. army.
N. Kanesa-Thasan and colleagues at the Walter Reed Army Institute of Research tested the vaccine formulations in 40 volunteers with no immunity to flavivirus, in a randomized, controlled, double-blind study.
Five volunteers each were vaccinated with a single subcutaneous dose against dengue-1, dengue-2, dengue-3, or dengue-4; 10 were given a tetravalent vaccine with all four viruses, and 10 were given the vaccine vehicle alone.
Dengue-1, dengue-2, dengue-3, and dengue-4 vaccine recipients reported similar rates of headache, malaise, and eye pain, reported Kanesa-Thasan et al.
Of five subjects who developed fever eight to 10 days post-vaccination, four were from the tetravalent group. Tetravalent vaccines caused maculopapular rashes over the trunk and extremities, and transient neutropenia (white blood cells
All dengue-2, dengue-3, and dengue-4, and 60% of dengue-1 vaccine recipients developed neutralizing and/or immunoglobulin M antibodies. Dengue-3 and dengue-4 subjects were viremic between days 7-12, while dengue-1 and dengue-2 subjects were rarely viremic. All tetravalent vaccine recipients were viremic with dengue-3 virus and developed neutralizing antibodies to dengue-3.
- Dengue hemorrhagic fever, Uttaradit, Thailand.(Letters)
- Magazine article from: Emerging Infectious Diseases Patumanond, Jayanton Tawichasri, Chamaiporn Nopparat, Seree October 1, 2003 700+ words
...Cross-reaction between dengue virus and Japanese encephalitis...primarily young children, against dengue infection or at least reduce...incidence. The cohort of these vaccine recipients were then exposed to dengue infection later in life and...
- Dengue vaccine safety update.(Vaccines and Biomedicines)
- Magazine article from: WHO Drug Information June 22, 2004 700+ words
...sensitization to DHF is that dengue vaccines need to elicit a balanced immunity to all four dengue serotypes. The 4-5 year...risk of severe disease among vaccine recipients (1), but available information...The seroepidemiology of dengue fever should be determined...
- Abt Associates To Monitor Smallpox Vaccine Recipients For Department of Defense.
- Press release article from: Business Wire May 19, 2003 700+ words
...Monitoring and Communication With Vaccine Recipients Abt Associates Inc. announced that...or Web. This capability reassures vaccine recipients and establishes a simple direct method...monitoring approximately 2000 military vaccine recipients. More information on the project...
- Lack of Evidence of Endogenous Avian Leukosis Virus and Endogenous Avian...
- Magazine article from: Emerging Infectious Diseases Hussain, Althaf I. Shanmugam, Vedapuri Switzer, William M. Tsang, Shirley X. Fadly, Aly Thea, Donald Helfand, Rita Bellini, William J. Folks, Thomas M. Heneine, Walid January 1, 2001 700+ words
...transmission of these retroviruses to vaccine recipients. We used serologic and molecular...either ALV or EAV infection in MMR vaccine recipients and provide support for current immunization...stabilizing agent (2). Exposure of vaccine recipients to contaminated vaccines has been...
- Influenza vaccine recipients more likely to have heart and lung conditions.
- Newspaper article from: Heart Disease Weekly April 6, 2003 700+ words
...001) than those without underlying chronic diseases. Vaccine recipients had fewer days in hospital, compared with non-recipients...researchers concluded that "the influenza and pneumococcal-vaccine recipients were older and had significantly more chronic lung and...
- Smallpox vaccine recipients should wait to give blood, FDA says.(Brief Article)
- Newspaper article from: Medical Letter on the CDC & FDA January 26, 2003 700+ words
...whichever is later. Anyone who has scratched off the scab should not give blood for 2 months after vaccination. * Vaccine recipients who suffer side effects from the vaccination should not give blood until 14 days after all those complications...
- Smallpox vaccine recipients should wait to give blood, FDA says.
- Newspaper article from: Blood Weekly January 23, 2003 700+ words
...whichever is later. Anyone who has scratched off the scab should not give blood for 2 months after vaccination. * Vaccine recipients who suffer side effects from the vaccination should not give blood until 14 days after all those complications...
- Nutritional support for vaccine recipients.(Literature Review & Commentary)
- Magazine article from: Townsend Letter for Doctors and Patients Gaby, Alan R. February 1, 2005 700+ words
Twenty-two British adults with relatively low plasma selenium concentrations were randomly assigned to receive, in double-blind fashion, 50 or 100 mcg/day of selenium or placebo for 15 weeks. All subjects received an oral live attenuated poliomyelitis vaccine after six weeks. Compared with placebo,
- Taipei City gov't expands list of vaccine recipients.
- Newspaper article from: China Post November 30, 2005 700+ words
(From China Post) Taipei City government yesterday announced that it will be expanding people's eligibility to receive flu vaccines effective immediately as part of the city's efforts to prevent bird flu. Besides the children and the elderly, patients suffering from heavy injuries, the physically
- Orkand Teams With AMCI On Smallpox Vaccine Tracking Contract; Ohio Department...
- Press release article from: Business Wire February 21, 2003 700+ words
Business Editors/Health/Medical Writers FALLS CHURCH, VaBUSINESS WIREFeb. 21, 2003 The Orkand Corporation has partnered with Atlantic Management Center, Inc. (AMCI), to support AMCI's newly awarded contract with the Ohio Department of Health to develop and implement a program of registration and
Source: HighBeam Research, Five Vaccine Formulations Safe, Immunogenic In Humans.(Brief Article)