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Antiretroviral Treatment Improves Neurocognitive Function In Women.
2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Highly active antiretroviral therapy (HAART) can prevent HIV related cognitive impairment in women, suggest new study results.
R.A. Cohen and colleagues at Brown University, Rhode Island, evaluated the neurocognitive function of severely immune-impaired [HIV.sup.+] women treated with HAART compared with untreated women.
They found that women treated with a HAART regimen had significantly enhanced neurocognitive function compared with their untreated counterparts, and that functional improvements increased with the length of HAART treatment.
For women with immune CD4 cell counts reduced to below 100 x [10.sup.6] cells per liter of blood, HAART led to strongly improved scores on a number of psychomotor and cognitive tests, study data showed. The most substantial improvements were observed in women treated with HAART for more than 18 months, Cohen et al. said. By contrast, women not treated with HAART displayed progressive degradation in neurocognitive functioning.
The neurological benefits of HAART treatment were unaffected by other clinical variables and risk factors. Cohen et al. noted. Illicit drug use and depression did not impair ...
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Source: HighBeam Research, Antiretroviral Treatment Improves Neurocognitive Function In Women.