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Patent Granted For DNA Vaccine Technology.(Brief Article)

Vaccine Weekly

| April 18, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 APR 18 - (NewsRx.com & NewsRx.net) --

The Immune Response Corp. (IMNR) announced March 30, 2001, that it has received U.S. Patent Number 6,207,645 expanding coverage relating to its immune-based therapy for rheumatoid arthritis, Ravax(TM).

The recently issued patent has specific claims covering immunization using DNA vaccines that are designed to synthesize the T-cell receptor (TCR) V(beta) specific peptides in situ, in contrast to immunizing directly with the TCR peptides themselves. The patent also includes specific claims for DNA vaccines encoding key superantigen protein sequences from the V(beta) 3, V(beta) 14, and V(beta) 17 regions of the TCR present on the surface of these pathogenic T cells thought to be associated with rheumatoid arthritis.

The company believes that vaccination with Ravax may inhibit the disease-associated T cells that cause rheumatoid arthritis, and prevent further damage in patients suffering from the disease.

"This recent issuance is a key patent in that it extends previous coverage ...

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Source: HighBeam Research, Patent Granted For DNA Vaccine Technology.(Brief Article)

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