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2001 APR 18 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Researchers working in Thailand have determined that vaccinating children with combined diphtheria, tetanus, and pertussis vaccine and Haemophilus influenzae type b conjugate vaccine (PRP-T) is just as safe and effective as giving the two vaccines separately.
S. Lolekha and colleagues randomized 126 infants to receive either the combined vaccine or separate administration at the same time at two, four, and six months of age. Their findings were published in the Journal of Tropical Pediatrics.
Both vaccine approaches had a similar safety profile, and side effects were minor, consisting mostly of pain, redness, and low-grade fever ("Safety and immunogenicity of combined or associated administration of PRP-T vaccine with diphtheria, tetanus and pertussis vaccine in Thai children," J Trop Pediatr, 2001;47(1):24-29).
"With respect to immunogenicity, response to PRP-T vaccine was good," noted Lolekha et al. "Following just two doses, all infants achieved anti-PRP ...
Source: HighBeam Research, Simultaneous Vaccination Against DTP, Hib Is Safe And...