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Rotavirus Vaccine Limits Duration Of Sapporo-Like Virus Diarrhea.(Brief Article)
2001 APR 18 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Rotavirus vaccine appears to shorten the duration of gastroenteritis caused by Sapporo-like viruses (SLVs), say researchers working in Finland.
SLV occurs worldwide and peaks from March to May, as does rotavirus, but knowledge of SLV is limited outside Japan, said X.L. Pang and colleagues.
They collected stool samples from 1,432 episodes of gastroenteritis during a trial of rotavirus vaccine and used reverse transcriptase polymerase chain reaction (PCR) assay to identify which cases were caused by SLV. The assay used new primers specific for Sapporo virus genetic clusters.
SLV contributed to gastroenteritis in 9.2% of cases and was the sole causative agent in 5.6% of cases, reported Pang et al. Its chief symptom is diarrhea.
Although children receiving rotavirus vaccine had a similar incidence of SLV compared to those receiving placebo, the vaccine did appear to limit duration of SLV (P=0.0008) ("Effect of rotavirus vaccine on Sapporo virus gastroenteritis in Finnish infants," Pediatric Infectious Disease Journal, March 2001;20:295-300).
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Source: HighBeam Research, Rotavirus Vaccine Limits Duration Of Sapporo-Like Virus...