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Disorder Linked To Obesity In Premenopausal Women.(sleep apnea )
2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Susan Hasty, staff medical writer - A multicenter study has found that sleep apnea in women is associated with obesity and menopause, and that postmenopausal women on hormone replacement therapy have a reduced risk for sleep-disordered breathing.
E.O. Bixler and colleagues at Pennsylvania State University, the University of Pennsylvania, and in Madrid, Spain, evaluated a random sample of 16,583 men (4,364) and women (12,219), age 20 to 100 years, for the prevalence of sleep apnea. In a second phase of the study, 1,000 women and 741 men were evaluated overnight in a sleep laboratory.
"The results of our study indicated that, for clinically defined sleep apnea (apnea/hypopnea index [greater than or equal to] 10 and daytime symptoms), men had a prevalence of 3.9% and women 1.2%, resulting in an overall ratio of sleep apnea for men to women of 3.3:1 (p=0.0006)," Bixler et al. reported.
Premenopausal women and postmenopausal women on hormone replacement therapy (HRT) had similar low prevalences, 0.6% and 0.5%, respectively. Additionally, the sleep apnea found in these two groups was associated exclusively with obesity (body mass index, BMI [greater than or equal to] 32.3 kg/[m.sup.2]), the researchers said.
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