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2001 APR 5 - (NewsRx.com & NewsRx.net) -- According to a study in the American Journal of Clinical Nutrition, soy isoflavones have a modest cholesterol-lowering effect in postmenopausal women.
Several clinical studies have examined the effect of soy protein and soy-derived isoflavones in the context of the prevention of cardiovascular disease (CVD). Christopher D. Gardner et al. studied soy protein with or without soy isoflavones to determine if the lipid-lowering effect of soy could be specifically attributed to the isoflavone-containing fraction.
Soy consumption in two groups of postmenopausal women was compared to a control group who consumed milk protein. The reduction in low-density lipoprotein (LDL) and cholesterol was greatest among those who consumed soy protein with isoflavones. However, an unexpected and similar LDL cholesterol reduction in the milk protein (control) group suggested that the reductions attributed to soy isoflavones may be non-specific ("The effect of soy protein with or without isoflavones relative to milk protein on plasma lipids in hypercholesterolemic postmenopausal women," Am J Clin Nutr, 2001;73:728-35).
The 94 postmenopausal women who participated in the study were healthy nonsmokers who had not ...