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Vitamins C And E Combination Fights Side Effects Of Radiation Treatment For Cancers In Pelvic Area.
2001 APR 5 - (NewsRx.com & NewsRx.net) -- A study involving 20 individuals suffering from chronic radiation proctitis showed that a daily regimen of vitamins E and C substantially reduced or eliminated the symptoms of the illness.
This condition has traditionally been treated with anti-inflammatory agents without satisfactory results. Results of the study appear in the April 2001 issue of The American Journal of Gastroenterology.
Radiation therapy is commonly used to treat patients with cancers of the prostate, cervix, and endometrial cancers. Radiation therapy is effective in killing cancer cells but the therapy also damages some neighboring, non-cancerous cells. As a result, oxygen free radicals form and patients experience the symptoms of proctitis. The symptoms, including diarrhea, pain, bleeding, and incontinence, usually clear up within a few weeks of the last radiation treatment. However, the symptoms do not clear up in 10%-20% of the patients. Still other patients develop the symptoms months or years after the initial radiation exposure.
"Our study showed that we can harness the potent antioxidant properties of the vitamins to repair cell damage and bring relief to many people who suffer from the persistent, lifestyle-altering symptoms of chronic radiation proctitis," said Dr. Keith Bruninga, gastroenterologist at Rush Presbyterian-St. Luke's Medical Center, Chicago, Illinois, and one of the co-authors of the paper.
While the use of the vitamins has been shown in the past to prevent tissue damage associated with radiation injury, the effect of the vitamins in the treatment of chronic radiation proctitis had not been studied before.
Radiation treatment causes oxygen free radicals to form from cells that have been injured by radiation. Oxygen free radicals are highly active molecules that react with cells by changing or damaging their structure. The formation of the oxygen free radicals increases the amount of injury to the cells and results in a chronic condition as blood flow to the cells is decreased.
Vitamin E is a potent antioxidant that can react with damaging oxygen free radicals. Vitamin C in combination with E increases the effects of vitamin E. The researchers ...
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...acute radiation enteritis [1,2]. Chronic radiation enteritis may be diagnosed if symptoms...treatment [4]. The incidence of chronic radiation enteritis is as low as 0.5% to...those with documented symptoms of chronic radiation enteritis as identified from physicians...
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...use as a preparatory regime in bone marrow transplantation, Colomed is being studied for the treatment of chronic radiation proctitis (rectal inflammation after radiation), Antizol is an antidote for ethylene glycol (antifreeze) and methanol...
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...cell damage and bring relief to many people who suffer from the persistent, lifestyle-altering symptoms of chronic radiation proctitis," he said. X X X For young men who smoke and have high cholesterol and blood pressure, the writing is...
- TO BUSINESS AND MEDICAL:
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...cell damage and bring relief to many people who suffer from the persistent, lifestyle-altering symptoms of chronic radiation proctitis," he said. HEART RISKS: For young men who smoke and have high cholesterol and blood pressure, the writing...
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...cell damage and bring relief to many people who suffer from the persistent, lifestyle-altering symptoms of chronic radiation proctitis," he said. X X X For young men who smoke and have high cholesterol and blood pressure, the writing is...
Source: HighBeam Research, Vitamins C And E Combination Fights Side Effects Of Radiation...