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Tamoxifen Associated With Fatty Liver And Build-Up Of Intra-Abdominal Fat In Obese Patients.
2001 MAR 29 - (NewsRx.com & NewsRx.net) -- by Jennifer Webb, staff medical writer - Fatty liver and intra-abdominal fat accumulation are common in obese patients receiving tamoxifen for the treatment of breast cancer, study results indicate.
"Tamoxifen is a nonsteroidal anti-estrogenic drug used for adjuvant treatment of breast cancer and recently as a chemo-preventative agent for breast cancer and, on an investigational basis, for other cancers," reported J.G. Kral and colleagues from the Southern University of New York.
The researchers noted that case reports of hypertriglyceridemia and fatty liver disease have been demonstrated in tamoxifen users.
A cross-sectional study of 32 women who were taking tamoxifen and 39 controls was conducted to evaluate steatosis and distribution of adipose tissue. Computed tomography scan revealed more visceral adipose tissue (VAT) and more liver fat in the tamoxifen users than in the controls, reported Kral et al. ("Relationships between tamoxifen use, liver fat and body fat distribution in ...
- Tamoxifen Analogue Toremifene Not as Toxic to Liver.(breast cancer therapy...
- Newspaper article from: Drug Week January 26, 2001 700+ words
...disorders in breast cancer patients, according...new research. Fatty liver was observed...tamoxifen for breast cancer in order to identify fatty liver or NASH ("Toremifene-induced fatty liver and NASH in breast cancer patients with...
- "I beat breast cancer": one year after her frightening diagnosis, 38-year-old...
- Magazine article from: Redbook October 1, 2005 700+ words
...moving journey as a breast cancer patient. Here, she...adoptive parents! My breast cancer history didn't pose...things, from a slightly fatty liver caused by chemo to...women with metastatic breast cancer, but researchers needed...
- Fatty Liver
- Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Edgren, Altha January 1, 2006 700+ words
Fatty Liver Definition Fatty liver is the collection of excessive amounts of triglycerides and other fats inside liver cells. Description Also called steatosis, fatty liver can be a temporary or long-term condition, which is not harmful...
- Fatty liver disease on rise, can lead to cirrhosis, death.
- Newspaper article from: Knight Ridder/Tribune News Service Uhlenhuth, Karen June 16, 2003 700+ words
...high cholesterol _ add one more: fatty liver disease. The presence of too much fat...prevalent than we understood before." Fatty liver disease gained a name and definition...of Americans are afflicted with it. Fatty liver develops in an estimated 20 percent...
- New fatty liver study findings recently were published by researchers at...
- Newspaper article from: Gastroenterology Week June 1, 2009 700+ words
...and noninvasive testing on diagnosing fatty liver disease and with satisfied sensitivity...specificity. The sonographic diagnosis of fatty liver is usually made by radiologists who...to observe the macroscopic changes on fatty liver," investigators in Jinan, People...
- Epidemiology of fatty liver in a hospital-based study in Taiwan.
- Magazine article from: Southern Medical Journal Lai, Shih-Wei Tan, Chee-Keong Ng, Kim-Choy November 1, 2002 700+ words
...study was to assess the epidemiology of fatty liver in Taiwan. Methods. We retrospectively...was 49.2 years. The prevalence of fatty liver was 36.9% in all subjects, and prevalence...that the significant factors related to fatty liver were male sex, obesity, hyperglycemia...
- Cellular stress causes fatty liver disease in mice.
- Newspaper article from: Diabetes Week December 22, 2008 700+ words
...critical cellular housekeeping process and fatty liver disease, a condition that causes fat...for understanding and perhaps treating fatty liver disease, which is the most common form...in three American adults. Although fatty liver itself does not necessarily cause illness...
- Fatty Liver Blocks Mastastasis.
- Newspaper article from: Angiogenesis Weekly Nichols, Sonia February 23, 2001 700+ words
...cancer lesions, new research has found. Fatty liver, or hepatic steatosis, a condition...Hepato-Gastroenterology, rats with fatty liver who were injected with rat colorectal...metastatic liver lesions than the non-fatty liver control rats. H. Karube and coworkers...
