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Don't Start Vaccination Too Soon Or Finish Too Early.(Brief Article)
2001 APR 11 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - Starting the three-dose course of polio vaccination at the currently recommended age of six months and finishing at 18 months produces the most persistent antibody response, say researchers working in Finland.
H. Sormunen and colleagues tested several regimens for immunization with inactivated poliovirus vaccine (IPV) and found that while all produced satisfactory antibody levels, some were more ideal than others.
"The age of the child at the first dose (one to four months) and the interval between the first and second doses (two to four months) influenced the initial responses in a serotype-dependent manner," reported Sormunen and team.
They found that although all five groups of children had adequate protection after the third vaccine dose, those given the third dose at 18 months had higher persisting antibody levels than those who got their last dose at 12 months.
At age three years, children who had received their first dose of IPV at the recommended age of six months had the highest persisting antibody levels against PV1 and PV2 but not PV3 ("Age- and dose-interval-dependent antibody responses to inactivated poliovirus vaccine," J Med Virol, April ...
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- Newspaper article from: Vaccine Weekly November 13, 2002 700+ words
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